Factors associated with the initiation of alcohol, psychopharmaceuticals and other psychoactive substance use during the covid-19 pandemic

Authors

DOI:

https://doi.org/10.21527/2176-7114.2026.51.15415

Keywords:

Covid-19, Psychopharmaceuticals, Substance use, Universities, Mental health

Abstract

The emerging crisis of the COVID-19 pandemic brought several challenges related to mental health. As a response to this sudden situation, the general population may have presented psychological symptoms, including the use of psychoactive substances. This study aimed to identify factors associated with the initiation of alcohol, psychopharmaceuticals, and/or other psychoactive substance use during the pandemic. This was a cross-sectional observational study conducted between April and September 2021 with 2,469 participants (students, professors, and staff) from four federal universities located in the Central-West region of Brazil. Logistic regression analysis was performed to estimate odds ratios. Overall, approximately one-quarter of participants reported initiating substance use during the COVID-19 pandemic. Psychopharmaceuticals were the most frequently reported substances among both students and professors/staff, followed by alcohol. Among students, the initiation of alcohol use was associated with living with friends/roommates, belonging to a risk group for severe COVID-19 illness, and having experienced domestic violence during social distancing measures. Different individual and social factors were associated with the initiation of substance use during the pandemic, with younger age and student status being related to the onset of illicit substance use.

References

1. WHO. World Health Organization. COVID-19 Response Fund. Acessed July 7, 2022 [Internet]. Available from:. https://COVID19.who.int/t/

2. Ayittey F, Ayittey MK, Chiwero NB, Kamasah JS, Dzuvor C. Economic impacts of Wuhan 2019-nCoV on China and the world. (2020). J. Med. Virol. 2020;92(5):473–475. DOI: https://doi.org/10.1002/jmv.25706

3. Kathirvela N. Post COVID-19 pandemic mental health challenges. Asian J Psychiatr. 2020;53:102430. DOI: https://doi.org/10.1016/j.ajp.2020.102430

4. Chodkiewicz J, Talarowska M, Miniszewska J, Nawrocka N, Bilinski P. Alcohol consumption reported during the COVID-19 pandemic: The initial stage. IJERPH. 2020;17(13):4677. DOI: https://doi.org/10.3390/ijerph1713467 7

5. Banerjee D, Rai M. (2020). Social isolation in COVID-19: the impact of loneliness. Int J Soc Psychiatry. 2020;66(6):525–527. DOI: https://doi.org/10.1177/0020764020922269

6. María-Ríos CE, Morrow JD. Mechanisms of shared vulnerability to post-traumatic stress disorder and substance use disorders. Front. Behav. Neurosci. 2020;14: 6. DOI: https://doi.org/10.3389/fnbeh.2020.00006

7. Galea S, Merchant RM, Lurie N. The Mental Health Consequences of COVID-19 and Physical Distancing: The Need for Prevention and Early Intervention. JAMA Intern Med. 2020;180(6):817–818. DOI: https://doi.org/10.1001/jamainternmed.2020.1562

8. Farhoudian A, et al. A global survey on changes in the supply, price, and use of illicit drugs and alcohol, and related complications during the 2020 COVID-19 pandemic. Front. Psychiatry. 2021;12:646206. DOI: https://doi.org/10.3389/fpsyt.2021.646206

9. Taylor S, Paluszek MM, Rachor GS, McKay D, Asmundson D. (2021). Substance use and abuse, COVID-19-related distress, and disregard for social distancing: a network analysis. Addict Behav. 2021;114:106754. DOI: https://doi.org/10.1016/j.addbeh.2020.106754

10. Fontes BA, Jacinto PBS, Rocha RVS. Consumption of benzodiazepine anxiolytics during the COVID-19 pandemic: a remote study with university students. Sapienza. 2022;3(1):34–44. DOI: https://doi.org/10.51798/sijis.v3i1.203

11. Milani SA, et al. Trends in the use of benzodiazepines, z-hypnotics, and serotonergic drugs among US women and men before and during the COVID-19 pandemic. JAMA Netw Open; 2021;4(10):e2131012. DOI: https://doi.org/10.1001/jamanetworkopen.2021.31012

12. Campos B, Tchalekian B, Paiva V. Violência contra a mulher: vulnerabilidade programática em tempos de Sars-cov-2/ COVID-19 em São Paulo. Psicol. Soc. 2020;32: e020015. DOI: https://doi.org/10.1590/1807-0310/2020v32240336

13. Silva, AF, et al. Marital violence precipitating/intensifying elements during the COVID-19 pandemic. Cien Saude Colet. 2020;25(9):3475-3480. DOI: https://doi.org/10.1590/1413-81232020259.16132020

14. Babicki M, Piotrowski P, Mastalerz-Migas, A. Assessment of Insomnia Symptoms, Quality of Life, Daytime Sleepiness, and Psychoactive Substance Use among Polish Students: A Cross-Sectional Online Survey for Years 2016–2021 before and during COVID-19 Pandemic. J. Clin. Med. 2022;11(8):2106. DOI: https://doi.org/10.3390/jcm11082106

15. Lechner WV, Laurene KR, Patel S, Anderson M, Grega C, Kenne DR. Changes in alcohol use as a function of psychological distress and social support following COVID-19 related University closings. Addict Behav. 2020;110:106527. DOI: https://doi.org/10.1016/j.addbeh.2020.106527

16. Liyanage S, et al. Prevalence of Anxiety in University Students during the COVID-19 pandemic: a systematic review. Int. J. Environ. Res. Public Health. 2022;19(1):62. DOI: https://doi.org/10.3390/ijerph19010062

17. Torres AG, et al. COVID-19 e Saúde Mental de Universitários: Revisão Integrativa Internacional. Rev. Psicol. Saud. 2021;13(4):183–197. DOI: https://doi.org/10.20435/pssa.v13i4.1567

18. MacMillan T, Corrigan MJ, Coffey K, Tronnier CD, Wang D, Krase K. Exploring Factors Associated with Alcohol and/or Substance Use During the COVID-19 Pandemic. Int J Ment Health Addict. 2021;20(3):1814–1823. DOI: https://doi.org/10.1007/s11469-020-00482-y

19. Christoffersen LAN, Mortensen EL, Becker U, Osler M, Sorensen HJ, Flensborg-Madsen T. Age at onset and age at treatment of alcohol use disorders: Associations with educational level and intelligence. Alcohol. 2021;95:7-14. DOI: https://doi.org/10.1016/j.alcohol.2021.04.005

20. Candido FJ, et al. The use of drugs and medical students: a literature review. Rev Assoc Med Bras. 2018;64(5):462-468. DOI: https://doi.org/10.1590/1806-9282.64.05.462

21. Simplício MPT, Silva LB, Juvanho L, Priore SE, Franceschini SC. Factors associated with alcohol, tobacco and illicit drug use among Brazilian undergraduate students. Rev Bras Enferm. 2021;74(3):e20201244. DOI: https://doi.org/10.1590/0034-7167-2020-1244

22. Pirutinsky S, Cherniak A, Rosmarin D. COVID-19, mental health, and religious coping among american orthodox jews. J Relig Health. 2020;59(1):2288–2301. DOI: https://doi.org/10.1007/s10943-020-01070-z

23. Zacher H, Rudolph, C. Individual differences and changes in subjective wellbeing during the early stages of the COVID-19 pandemic. Am Psychol. 2020;76(1):50-62. DOI: https://doi.org/10.1037/amp0000702

24. Chae DH, et al. Vicarious Racism and Vigilance During the COVID-19 Pandemic: Mental Health Implications Among Asian and Black Americans. Public Health Rep. 2021;136(4):508-517. DOI: https://doi.org/10.1177/00333549211018675

25. Neves JA, Machado ML, Oliveira LD, Moreno YM, Medeiros MA, Vasconcelos FA. Unemployment, poverty, and hunger in Brazil in COVID-19 pandemic times. Rev. de Nutr. 2021;34:e200170. DOI: https://doi.org/10.1590/1678-9865202134e200170

26. Sacco MA, Caputo F, Ricci P. The impact of the COVID-19 pandemic on domestic violence: The dark side of home isolation during quarantine. Med Leg J. 2020;88(2):71-73. DOI: https://doi.org/10.1177/0025817220930553

27. Becker AS., et al. (2021). The impact on the mental health of university students undergoing remote digital education during social isolation. due to the COVID-19 pandemic: a systematic review. Revista AMRIGS. 2021;65(spe1):2-11. DOI: https://doi.org/10.1590/0103-11042022E114

28. Teodoro MLM, et al. Mental health in college students during COVID-19 pandemic. REFACS. 2021;9(2):372-82. DOI: https://doi.org/10.18554/refacs.v9i2.5409

29. Kohls E, Baldofski S, Moeller R. Mental Health, Social and Emotional Well-Being, and Perceived Burdens of University Students During COVID-19 Pandemic Lockdown in Germany. Front. Psychiatry. 2021;12:643957. DOI: https://doi.org/10.3389/fpsyt.2021.643957

30. World Health Organization. Who Coronavirus (COVID-19). 2022. Retrieved from https://COVID19.who.int/

31. Gritsenko V, Skugarevsky O, Konstantinov V, Khamenka N, Marinova T, Reznik A, Isralowitz R. COVID-19 fear, stress, anxiety, and substance use among russian and belarusian university students. Int J Ment Health Addict. 2020;19:2362–2368. DOI: https://doi.org/10.1007/s11469-020-00330-z

32. Salerno, J. P., Shrader, C. H., Algarin, A. B., Lee, J. Y., & Fish, J. N. Changes in alcohol use since the onset of COVID-19 are associated with psychological distress among sexual and gender minority university students in the US. Drug Alcohol Depend. 2021;221:108594. https://doi.org/10.1016/j.drugalcdep.2021.108594

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Published

2026-03-02

How to Cite

Baptista, C. J., Escalda, P. M. F., Martins, A. M., Bittencourt, M. N., & Chaves, M. R. de C. (2026). Factors associated with the initiation of alcohol, psychopharmaceuticals and other psychoactive substance use during the covid-19 pandemic. Revista Contexto & Saúde, 26(51), e15415. https://doi.org/10.21527/2176-7114.2026.51.15415

Issue

Vol. 26 No. 51 (2026): 2026

Section

ORIGINAL ARTICLE

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Copyright (c) 2026 Cremildo João Baptista, Patrícia Maria Fonseca Escalda, Alberto Mesaque Martins, Marina Nolli Bittencourt, Monalisa Rocha de Campos Chaves

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