Infection and associated factors in children and adolescents undergoing antineoplastic chemotherapy
DOI:
https://doi.org/10.21527/2176-7114.2024.48.14705Keywords:
Infections, Neoplasms, Child Health, Adolescent HealthAbstract
Objective: To evaluate the infection prevalence in children and adolescents with cancer undergoing chemotherapy and identify the associated factors. Methods: This cross-sectional study reviewed 59 medical records of children and adolescents with cancer receiving chemotherapy in the pediatric oncology ward at a referral center in Campina Grande, Paraíba. We conducted descriptive and multivariate analyses using Poisson regression. Results: The study identified a 47.5% infection prevalence during the first cycle of chemotherapy in children and adolescents with cancer. Significant risk factors for infection included invasive ventilation, non-invasive ventilation, and corticosteroid use. Significant symptoms and signs included diarrhea, adventitious sounds, dyspnea, headache, altered mental and behavioral states, fever, tachypnea, hepatomegaly, and splenomegaly. Conclusion: We found a high infection prevalence during the first cycle of chemotherapy. This complication can delay cancer treatment, promote tumor growth, and reduce the effectiveness of the therapy used.
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