Pre- and post-chemotherapy nutritional status in women with breast cancer: a systematic review
DOI:
https://doi.org/10.21527/2176-7114.2023.47.13038Keywords:
Nutrition; breast neoplasm; chemotherapy.Abstract
Introduction: Breast cancer (BC) is the malignant neoplasm with highest incidence and mortality among women worldwide. Nutritional status (NS) before and after chemotherapy treatment can be decisive for prognosis and survival of the patient with BC. Objective: Systematic review of the NS before and after chemotherapy in women with BC. Methods: An extensive search on Pubmed, Web of Science, and Scopus databases was conducted. It was limited to manuscripts published until 2020 using the Boolean method with the following combinations of descriptors: “breast cancer” AND “nutritional status” AND “chemotherapy”. Results: A total of 12 articles were included in this review. Two studies with patients diagnosed with eutrophic and 10 studies with overweight patients addressed pre-chemotherapy NS. For post-treatment NS, nine studies enrolled overweight patients, two with eutrophic patients and one with patients at nutritional risk. Conclusion: Several studies confirm the association of BC and overweight/obesity with increased prevalence of the disease, poor prognosis, and reduced survival after the end of the treatment. Current data support the need for interventions in the patients’ lifestyle. Further studies on the association between interventions in BC should be conducted in order to form a larger body of evidence.
References
Capelari P, Ceni GC. Feeding behavior and nutritional profile of cancer patients in drug therapy. Demetra. 2018;13(1):223-240.
Rocha ME, Silva LN, Soares PR, Pacheco Filho RT, Queiroz VCJ, Eleutério TDP, et al. Câncer de mama: caracterização quanto à idade e aos aspectos tumorais (tipo de tumor e extensão). Brazilian J Dev. 2020;6(1):2.375-2.387.
Instituto Oncoguia. Quimioterapia para Câncer de Mama [Internet]. 2017. Available from: http://www.oncoguia.org.br/conteudo/quimioterapia-para-cancer-de-mama/1405/265/
Monteiro DLM, Trajano AJB, Menezes DCS, Silveira NLM, Magalhães AC, Miranda FRD de, et al. Câncer de mama na gravidez e quimioterapia: revisão sistemática. Rev Assoc Med Bras. 2013;59(2):174-180.
Argilés M. Cancer-associated malnutrition. Eur J Oncol Nurs. 2005;9:39-50.
Ravasco P, Monteiro-Grillo I, Vidal PM, Camilo ME. Impact of nutrition on outcome: A prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy. Head Neck. 2005;27(8):659-668.
Wie GA, Cho YA, Kim SY, Kim SM, Bae JM, Joung H. Prevalence and risk factors of malnutrition among cancer patients according to tumor location and stage in the National Cancer Center in Korea. Nutrition. 2010;26(3):263-268.
Anderson B, Connor JP, Andrews JI, Davis CS, Buller RE, Sorosky JI, et al. Obesity and prognosis in endometrial cancer. Am J Obs Gynecol. 1996;174(4):1.171-1.178.
Majed B, Moreau T, Senouci K, Salmon RJ, Fourquet A, Asselain B. Is obesity an independent prognosis factor in woman breast cancer? Breast Cancer Res Treat. 2008;111(2):329-342.
Tokunaga M, Hiki N, Fukunaga T, Ogura T, Miyata S, Yamaguchi T. Effect of individual fat areas on early surgical outcomes after open gastrectomy for gastric cancer. Br J Surg. 2009;96(5):496-500.
Moher D, Liberati A, Tetzlaff J, Altman DG. The PRISMA group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. BMJ. 2009;339(7716):332-336.
Kmet LM, Lee RC, Cook LS. Standard quality assessment criteria for evaluating primary research papers from a variety of fields. HTA Initiat. 2004;(February):1-22.
Lima MTM, Maruyama TC, Custódio IDDi, Marinho EDC, Ferreira IB, Crispim CA, et al. The impact of a higher eating frequency on the diet quality and nutritional status of women with breast cancer undergoing chemotherapy. Br J Nutr. 2020;123(4):410-418.
Oba T, Maeno K, Takekoshi D, Ono M, Ito T, Kanai T, et al. Neoadjuvant chemotherapy-induced decrease of prognostic nutrition index predicts poor prognosis in patients with breast cancer. BMC Cancer. 2020;20(1):1-10.
Custódio IDD, Franco F de P, Marinho E da C, Pereira TSS, Lima MTM, Molina MDCB, et al. Prospective analysis of food consumption and nutritional status and the impact on the dietary inflammatory index in women with breast cancer during chemotherapy. Nutrients. 2019;11(11):1-15.
Ambrosi C, Di Pietro PF, Vieira FGK, Rockenbach G, Boaventura BCB, Galvan D, et al. Efeito do tratamento antineoplásico adjuvante na mudança de peso corporal em mulheres com câncer de mama. Sci Med. 2012;22(3).
Brain EGC, Mertens C, Girre V, Rousseau F, Blot E, Abadie S, et al. Impact of liposomal doxorubicin-based adjuvant chemotherapy on autonomy in women over 70 with hormone-receptor-negative breast carcinoma: A French Geriatric Oncology Group (GERICO) phase II multicentre trial. Crit Rev Oncol Hematol. 2011;80(1):160-170.
Hurria A, Hurria A, Zuckerman E, Panageas KS, Fornier M, D’Andrea G, et al. A prospective, longitudinal study of the functional status and quality of life of older patients with breast cancer receiving adjuvant chemotherapy. J Am Geriatr Soc. 2006;54(7):1.119-1.124.
Custódio IDD, Marinho EDC, Gontijo CA, Pereira TSS, Paiva CE, De Maia YCP. Impact of chemotherapy on diet and nutritional status of women with breast cancer: A prospective study. PLoS One. 2016;11(6):1-20.
Georges SO, Braga CC, Martins KA. Weight variation gain and chemotherapy in women having breast cancer treated in the public health system. Mundo da Saúde. 2014;38(3):260-268.
Cisneros KM, Romero JE, Genaro Guevara Torres A, Valencia ME, Olivia Méndez Estrada R, Ortiz OT, et al. Impacto del tratamiento antineoplásico en el estado nutricional en pacientes con cáncer de mama. Nutr Hosp. 2014;30(4):876-882.
Liz S de, Vieira FGK, de Assis MAA, Cardoso AL, Pazini CPL, Pietro PF Di. Adherence to the WCRF/AICR for Women in Breast Cancer Adjuvant Treatment submitted to Educational Nutritional Intervention. Nutr Cancer. 2018;70(5):737-747.
Harvie MN, Howell A, Thatcher N, Baildam A, Campbell I. Energy balance in patients with advanced NSCLC, metastatic melanoma and metastatic breast cancer receiving chemotherapy – A longitudinal study. Br J Cancer. 2005;92(4):673-680.
Boltong A, Aranda S, Keast R, Wynne R, Francis PA, Chirgwin J, et al. A prospective cohort study of the effects of adjuvant breast cancer chemotherapy on taste function, food liking, appetite and associated nutritional outcomes. PLoS One. 2014;9(7):1-9.
Cicco P De, Catani MV, Gasperi V, Sibilano M, Quaglietta M, Savini I. Nutrition and breast cancer: A literature review on prevention, treatment and recurrence. Nutrients. 2019;11(7):1.514.
Pischon T, Nimptsch K. Obesity and cancer. 1st ed. Cham: Springer International Publishing; 2015. 256p.
Silva HR, Costa RHF, Neto JCP, de Macedo Júnior CAA, Pacheco NI, da Silva Brito N, et al. Prevalence and risk factors association between obesity and breast cancer. Res Soc Dev. 2020;9(3).
Figueiredo ACDS, Ferreira RNF, Duarte MAG, Coelho AF, Cabral KMA de A. Prevalência da obesidade em mulheres tratadas de câncer de mama numa UNACOM em Juiz de Fora. Rev Bras Mastol. 2016;26(4):169-174.
Bhaskaran K, Douglas I, Forbes H, Dos-Santos-Silva I, Leon DA, Smeeth L. Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults. Lancet. 2014;384(9945):755-765.
Neuhouser ML, Aragaki AK, Prentice RL, Manson JAE, Chlebowski R, Carty CL, et al. Overweight, obesity, and postmenopausal invasive breast cancer risk: A secondary analysis of the women’s health initiative randomized clinical trials. JAMA Oncol. 2015;1(5):611-621.
Buch K, Gunmalm V, Andersson M, Schwarz P, Brøns C. Effect of chemotherapy and aromatase inhibitors in the adjuvant treatment of breast cancer on glucose and insulin metabolism – A systematic review. Cancer Med. 2019;8(1):238-245.
Caan BJ, Kwan ML, Hartzell G, Castillo A, Slattery ML, Sternfeld B, et al. Pre-diagnosis body mass index, post-diagnosis weight change, and prognosis among women with early stage breast cancer. Cancer Causes Control. 2008;19(10):1.319-1.328.
Loehder P, Kümpel DA, Hartmann V. Nutritional status of women on chemotherapy at a hospital in the north of the state of Rio Grande do Sul. BRASPEN J. 2019;34(1):83-87.
Lima FEL de, Latorre MDRDDO, Costa MJDC, Fisberg RM. Diet and cancer in Northeast Brazil: Evaluation of eating habits and food group consumption in relation to breast cancer. Cad Saúde Pública. 2008;24(4):820-828.
Harvie MN, Campbell IT, Baildam A, Howell A. Energy balance in early breast cancer patients receiving adjuvant chemotherapy. Breast Cancer Res Treat. 2004;83(3):201-210.
Oliveira DR de, Carvalho ESC, Campos LC, Leal JA, Sampaio EV, Cassali GD. Avaliação nutricional de pacientes com câncer de mama atendidas no Serviço de Mastologia do Hospital das Clínicas, Belo Horizonte (MG), Brasil. Cienc e Saúde Coletiva. 2014;19(5):1.573-.1.580.
Nechuta SJ, Caan BJ, Chen WY, Flatt SW, Lu W, Patterson RE, et al. The after Breast Cancer Pooling Project: Rationale, methodology, and breast cancer survivor characteristics. Cancer Causes Control. 2011;22(9):1.319-1.331.
Irwin ML, McTiernan A, Baumgartner RN, Baumgartner KB, Bernstein L, Gilliland FD, et al. Changes in body fat and weight after a breast cancer diagnosis: Influence of demographic, prognostic, and lifestyle factors. J Clin Oncol. 2005;23(4):774-782.
Chan DSM, Vieira AR, Aune D, Bandera E V., Greenwood DC, McTiernan A, et al. Body mass index and survival in women with breast cancer – systematic literature review and meta-analysis of 82 follow-up studies. Ann Oncol. 2014;25(10):1.901-1.914.
George SM, Bernstein L, Smith AW, Neuhouser ML, Baumgartner KB, Baumgartner RN, et al. Central adiposity after breast cancer diagnosis is related to mortality in the Health, Eating, Activity, and Lifestyle study. Breast Cancer Res Treat. 2014;146(3):647-655.
Miranda TV de, Neves FMG, Costa GNR, Souza MAM de. Estado nutricional e qualidade de vida de pacientes em tratamento quimioterápico. Rev Bras Cancerol. 2013;59(1):57-64.
Tartari RF, Busnello FM, Nunes CHA. Nutritional Profile of Patients Submitted to Chemotherapy in a Tertiary Outpatient Clinic. Rev Bras Cancerol. 2010;56(1):43-50.
Borges LR, Paiva SI, Silveira DH, Assunção MCF, Gonzalez MC. Can nutritional status influence the quality of life of cancer patients? Rev Nutr. 2010;23(5):745-753.
Felden JBB, Figueiredo ACL. Distribuição da gordura corporal e câncer de mama: um estudo de caso-controle no Sul do Brasil. Cien Saúde Colet. 2011;16(5):2.425-2.433.
Mobarakeh ZS, Mirzaei K, Hatmi N, Ebrahimi M, Dabiran S, Sotoudeh G. Dietary habits contributing to breast cancer risk among Iranian women. Asian Pacific J Cancer Prev. 2014;15(21):9.543-9.547.
Hajian-Tilaki K, Gholizadehpasha A, Bozorgzadeh S, Hajian-Tilaki E. Body mass index and waist circumference are predictor biomarkers of breast cancer risk in Iranian women. Med Oncol. 2011;28(4):1.296-1.301.
Brasil. Protocolos clínicos e diretrizes terapêuticas em Oncologia/Ministério da Saúde, Secretaria de Atenção à Saúde. Brasília: Ministério da Saúde; 2014.
Vieira SC, Lustosa AML, Barbosa CNB, Teixeira JMR, Brito LXE de, Soares LFM, et al. Oncologia Básica. 1. ed. Teresina: Fundação Quixote; 2012.
Anampa J, Makower D, Sparano JA. Progress in adjuvant chemotherapy for breast cancer: An overview. BMC Med. 2015;13(1).
Marx AG, Figueira PVG. Fisioterapia no câncer de mama. 1. ed. Barueri: Manole; 2017. 471p.
Kayl A, Meyers C. Side-effects of chemotherapy and quality of life in ovarian and breast cancer patients. Curr Opin Obstet Gynecol. 2006;18(1):24-28.
Saquib N, Flatt SW, Natarajan L, Thomson CA, Bardwell WA, Caan B, et al. Weight gain and recovery of pre-cancer weight after breast cancer treatments: Evidence from the women’s healthy eating and living (WHEL) study. Breast Cancer Res Treat. 2007;105(2):177-186.
Filho RK, Hajjar LA, Bacal F, Hoff PMG, Diz MDPS, Galas FRBG, et al. I Diretriz brasileira de cardio-oncologia da sociedade brasileira de cardiologia. Arq Bras Cardiol. 2011;96:1-52.
Giza DE, Iliescu G, Hassan S, Marmagkiolis K, Iliescu C. Cancer as a Risk Factor for Cardiovascular Disease. Curr Oncol Rep. 2017;19(6).
Jain D, Ahmad T, Cairo M, Aronow W. Cardiotoxicity of cancer chemotherapy: Identification, prevention and treatment. Ann Transl Med. 2017;5(17).
Garces Á, Garces I, Alexandre P, Mora R, Vieira F, Alves G, et al. Carboplatina e paclitaxel em primeira linha paliativa no tratamento de câncer de colo uterino avançado ou persistente recorrente: análise de uma série de casos do Instituto Nacional de Câncer do Brasil. Rev Bras Oncol Clínica. 2013;9(31):18-24.
Purcell SA, Elliott SA, Baracos VE, Chu QSC, Prado CM. Key determinants of energy expenditure in cancer and implications for clinical practice. Eur J Clin Nutr. 2016;70(11):1.230-1.238.
Fearon KCH, Glass DJ, Guttridge DC. Cancer cachexia: Mediators, signaling, and metabolic pathways. Cell Metab. 2012;16(2):153-166.
Straub RH, Cutolo M, Buttgereit F, Pongratz G. Energy regulation and neuroendocrine-immune control in chronic inflammatory diseases. J Intern Med. 2010;267(6):543-560.
Friesen DE, Baracos VE, Tuszynski JA. Modeling the energetic cost of cancer as a result of altered energy metabolism: Implications for cachexia. Theor Biol Med Model. 2015;12(1).
Scott HR, McMillan DC, Watson WS, Milroy R, McArdle CS. Longitudinal study of resting energy expenditure, body cell mass and the inflammatory response in male patients with non-small cell lung cancer. Lung Cancer. 2001;32(3):307-312.
Cao D xing, Wu G hao, Zhang B, Quan Y jun, Wei J, Jin H, et al. Resting energy expenditure and body composition in patients with newly detected cancer. Clin Nutr. 2010;29(1):72-77.
Ravasco P, Monteiro-Grillo I, Camilo M. Colorectal cancer: Intrinsic characteristics modulate cancer energy expenditure and the risk of cachexia. Cancer Invest. 2007;25(5):308-314.
Baracos VE. Metabolism and physiology. In: Del Fabbro E, Bruera E, Demark-Wahnefried W, Bowling T, Hopkinson J, editors. Nutrition and the Cancer Patient. Oxford University Press; 2010. p. 7-18.
Fearon K, Arends J, Baracos V. Understanding the mechanisms and treatment options in cancer cachexia. Nat Rev Clin Oncol. 2013;10(2):90-9.
Trutschnigg B, Kilgour RD, Morais JA, Lucar E, Hornby L, Molla H, et al. Metabolic, nutritional and inflammatory characteristics in elderly women with advanced cancer. J Geriatr Oncol. 2013;4(2):183-139.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Revista Contexto & Saúde
This work is licensed under a Creative Commons Attribution 4.0 International License.
Autores que publicam na Revista Contexto & Saúde concordam com os seguintes termos:
a) A submissão de trabalho(s) científico(s) original(is) pelos autores, na qualidade de titulares do direito de autor do(s) texto(s) enviado(s) ao periódico, nos termos da Lei 9.610/98, implica na cessão de direitos autorais de publicação na Revista Contexto e Saúde do(s) artigo(s) aceitos para publicação à Universidade Regional do Noroeste do Estado do Rio Grande do Sul, autorizando-se, ainda, que o(s) trabalho(s) científico(s) aprovado(s) seja(m) divulgado(s) gratuitamente, sem qualquer tipo de ressarcimento a título de direitos autorais, por meio do site da revista e suas bases de dados de indexação e repositórios, para fins de leitura, impressão e/ou download do arquivo do texto, a partir da data de aceitação para fins de publicação. Isto significa que, ao procederem a submissão do(s) artigo(s) à Revista Contexto e Saúde e, por conseguinte, a cessão gratuita dos direitos autorais relacionados ao trabalho científico enviado, os autores têm plena ciência de que não serão remunerados pela publicação do(s) artigo(s) no periódico.
b). Autores mantém os direitos autorais e concedem à revista o direito de primeira publicação, com o trabalho simultaneamente licenciado sob a Licença Creative Commons Attribution que permite o compartilhamento do trabalho com reconhecimento da autoria e publicação inicial nesta revista.
c). Autores têm autorização para assumir contratos adicionais separadamente, para distribuição não-exclusiva da versão do trabalho publicada nesta revista (ex.: publicar em repositório institucional ou como capítulo de livro), com reconhecimento de autoria e publicação inicial nesta revista.
d. Autores têm permissão e são estimulados a publicar e distribuir seu trabalho online (ex.: em repositórios institucionais ou na sua página pessoal) a qualquer ponto antes ou durante o processo editorial, já que isso pode gerar alterações produtivas, bem como aumentar o impacto e a citação do trabalho publicado (Veja O Efeito do Acesso Livre).
