ELABORAÇÃO E VALIDAÇÃO DE MATERIAL DIDÁTICO PARA ESCOLHA DE EXCIPIENTES DE CÁPSULAS PREPARADAS MAGISTRALMENTE
ELABORATION AND VALIDATION OF TEACHING MATERIAL FOR CHOOSING FILLERS FROM CAPSULES MASTERFULLY PREPARED
DOI:
https://doi.org/10.21527/2176-7114.2021.43.11467Keywords:
Excipientes. Cápsulas duras. Incompatibilidade. Classificação biofarmacêutica. Material educativo.Abstract
ABSTRACT
Excipients are components fundamental components of a pharmaceutical preparation, stabilizing the active principle, favoring its solubility during the preparation process and its absorption after administration. However, the choice of these substance must be a careful process because they can interfere in the bioavailability of drugs and cause side effects. The objective of this study was to elaborate and validate an educational material to assist pharmacists in choosing the appropriate excipients for the preparation of magistral capsules. This questionnaire was sent to a group of judges, consisting of pharmacists with experience in area of pharmacotechnics. Based on the evaluations, the educational material on excipients was prepared and sent back to the judges for validation. The evaluations of the judges supported the preparation of educational material on excipients for the preparation of capsules following the criteria of the Biopharmaceutical Classification System. The material was validated, reaching the 70% concordance rate proposed in this study, and the suggestions considered pertinent were incorporated into the educational material. With the help of a panel of specialists in area of pharmacotechnics, a validated educational material was produced, containing important information for the choice of capsule excipients prepared masterfully. The educational material produced can represent an important resource to be used in continuing education activities for professionals working in manipulation pharmacies.
Keywords: Excipients. Hard capsules. Incompatibility. Biopharmaceutical Classification. Didactic material
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